BDBM50453821 CHEMBL4206831

SMILES CCC(=O)Nc1ccc(cc1)C(=O)Nc1ccc(Nc2ncc3N(C)C(=O)c4cc(C)ccc4N(C)c3n2)cc1

InChI Key InChIKey=KGXBCWANASZZQG-UHFFFAOYSA-N

Data  6 IC50  2 EC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50453821   

TargetAurora kinase A(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50453821(CHEMBL4206831)
Affinity DataIC50:  52nMAssay Description:Inhibition of recombinant full length His-tagged human Aurora A expressed in baculovirus expression system by Z'LYTE assayMore data for this Ligand-Target Pair
TargetAurora kinase A(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50453821(CHEMBL4206831)
Affinity DataEC50:  38nMAssay Description:Inhibition of Aurora A auto-phosphorylation in human HCT116 cells after 4 hrs by Western blot analysisMore data for this Ligand-Target Pair